The purpose of this study is to closely examine relationship of the system re-use intention depending on CRS technology acceptance. Accordingly, questionnaire was widely distributed to 160 CRS users by convenient sampling targeting people in charge of task among employees for airlines and travel agencies, who are working-level staffs for CRS. Among these things, totally 142 valid materials were used in analysis. The analytical data processing was utilized SPSSWIN VER 18.0 and AMOS 18.0. The findings can be summarized as follows. Influential variables in CRS technology acceptance had significant influence upon the perceived ease use, the perceived usability, and the re-use intention. Also, the significant positive(+) influence was revealed to be had upon the perceived usability by the perceived ease use and upon the re-use intention by the perceived usability and ease use.