Drillship has several large cranes to handle the various equipments for drilling work. These cranes are supported by crane pedestals which are installed on main deck. Two major loads, i.e., hull girder bending moment and crane operation loading shall be considered to confirm the structural strength in way of crane pedestal. In this paper, the fatigue analysis is performed for the structures in way of crane pedestal considering two(2) loads as mentioned in the above is introduced.