In this paper an attempt has been made to classify Asia land cover considering climatic and vegetative characteristics. The sub-class clustering based on the 13 MODIS land cover classes (except water) over Asia was performed with the climate map and the NOVI derived from SPOT 5 VGT D10 data. The unsupervised classification for the sub-class clustering was performed in each land cover class, and total 74 clusters were determined over the study area. Via these clusters, the annual variations (from 1999 to 2007) of precipitation rate and temperature were analyzed as an example by a simple linear regression model. The various annual variations (negative or positive pattern) were represented for each cluster because of the various climate zones and NOVI annual cycles. Therefore, the detailed land cover map as the classification result by the sub-class clustering in this study can be useful information in modelling works for requiring the detailed climatic and vegetative information as a boundary condition.