In this paper, we proposed a new design methodology to improve the classification performance of the Nearest Prototype Classifier which is one of the simplest classification algorithm. To optimize the position vectors of the prototypes in the nearest prototype classifier, we use the differential evolutionary algorithm. The optimized position vectors of the prototypes result in the improvement of the classification performance. The new method to determine the class labels of the prototypes, which are defined by the differential evolutionary algorithm, is proposed. In addition, the experimental application covers a comparative analysis including several previously commonly encountered methods.