The study is aimed at examining the interaction between mothers with high postpartum depression tendencies and their 6 to 8 month old infants. Thirty pairs of infants and mothers with high depression tendencies and another 30 pairs of infants and mothers with low depression scores on the EPDS and K-PSI were selected as the final research subjects from a total of 185 mother-child pairs. They visited a laboratory and agreed to a video-recording which focussed on their infant-mother interaction for approximately 30 minutes. In conclusion, the group of mothers with high depression tendencies showed less positive, and more intrusive interactions and their infants displayed less responsive, less positive expressions than the group of mothers with low depression tendencies. This study is meaningful in that it represents a rare attempt at a qualitative analysis research into the interactions between mothers with postpartum depression and their infants.