As multicultural family gradually increased, our society is changing towards multicultural society. This study tried to identify the factors related with social distance of adolescent of multicultural family. The participants were 568 middle school students living in S city, D and H county in Chungnam province. Data for the study were analyzed by frequency, mean comparison, correlation and regression analysis. The study results were summarized as follows. First, there were significant differences in social distance according to gender, school record, and place of residence. Second, there were significant differences in social distance according to degree of intimacy between general adolescents. Third, as a result of correlation analysis, the lower self-esteem was, the lower value orientation was, the lower cultural diversity was; the higher social distance is. Accordingly, social distance for adolescents had negative correlations with self-esteem, value orientation, and cultural diversity. Fourth, variables affecting social distance were gender, school record, family composition, place of residence, friend from multicultural family, intention to be a friend, experience of overseas travel, self-esteem, value orientation, cultural diversity. Among them, intention to be a friend was a main predictor.