In this paper, the thermal performance of a heat spreader module for CPV(Concentrating Photovoltaic) cooling is experimentally investigated. In order to evaluate the thermal performance of the heat spreader module which consists of a Metal PCB and an aluminum alloy heat spreader, experiments are conducted with varying the type of the metal PCB, the thickness of the heat spreader, the inclination angle, and the applied heat flux. To validate the experimental data, three dimensional numerical simulations are performed using the commercial simulation tool in the present work. The experimental results are compared with the corresponding numerical results and are in close agreement with the numerical results. From the experimental results, the temperature difference between the maximum temperature and the ambient temperature increases with decreasing the thickness of the heat spreader and with increasing the applied heat flux. Also, it is found that the inclination angle significantly affects the thermal performance of the heat spreader. the maximum temperature difference of the heat spreader with the horizontal orientation is much larger than that with the vertical orientation.