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서지반출
Linkage Disequilibrium and Effective Population Size in Hanwoo Korean Cattle
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  • Linkage Disequilibrium and Effective Population Size in Hanwoo Korean Cattle
  • Linkage Disequilibrium and Effective Population Size in Hanwoo Korean Cattle
저자명
Lee. S.H.,Cho. Y.M.,Lim. D.,Kim. H.C.,Choi. B.H.,Park. H.S.,Kim. O.H.,Kim. S.,Kim. T.H.,Yoon. D.,Hong. S.K.
간행물명
Asian-Australasian journal of animal sciences
권/호정보
2011년|24권 12호|pp.1660-1665 (6 pages)
발행정보
아세아태평양축산학회
파일정보
정기간행물|ENG|
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기타
이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

This study presents a linkage disequilibrium (LD) analysis and effective population size ($N_e$) for the entire Hanwoo Korean cattle genome, which is the first LD map and effective population size estimate ever calculated for this breed. A panel of 4,525 markers was used in the final LD analysis. The pairwise $r^2$ statistic of SNPs up to 50 Mb apart across the genome was estimated. A mean value of $r^2$ = 0.23 was observed in pairwise distances of <25 kb and dropped to 0.1 at 40 to 60 kb, which is similar to the average intermarker distance used in this study. The proportion of SNPs in useful LD ($r^2{geq}0.25$) was 20% for the distance of 10 and 20 kb between SNPs. Analyses of past effective population size estimates based on direct estimates of recombination rates from SNP data demonstrated that a decline in effective population size to $N_e$ = 98.1 occurred up to three generations ago.