This study was conducted to investigate the relationship between groundwater level change and a large earthquake using the data of groundwater and seawater intrusion monitoring wells in Jeju Island. Groundwater level data from 13 observation wells were analyzed with a large earthquake. The Earthquake occurred at Sumatra, Indonesia (Mw = 7.7) on 13 June 2010, and groundwater level anomalies which seems to be related to the Earthquake were found in 6 monitoring wells. They lasted for approximately 16~27 minutes and the range of groundwater level fluctuations were about 1.4~2.4 cm. Coefficient of determination values for relationship between groundwater level change and transmissivity, and response time were calculated to be $R^2$ = 0.76 and $R^2$ = 0.96, respectively. The study also indicates that the high transmissivity of aquifer showed the high goundwater level changes and longer response time.