This research intended to identify empirical recommendations for designing the DAISY service interface and used a case-based method. The case of this research was LG Digital Talking Book Library(http://voice.lg.or.kr) of LG Sangnam Library. A group of experts evaluated the current DAISY interface serviced by the web. After evaluation, major recommendations were suggested and these recommendations were used to develop the new DAISY Interface. Major recommendations were consideration of the reading flow of the screen-reader program, prevention of perception as an error about the time delay, development of web-based software, support for convenient functions and prevention of shortcut key overlap and so on.