In informational confusion of complicated society, self-esteem is considered as important psychological and temperamental factors for self-recognition and self-realization of youths. In this study, we found factors that affect self-esteem by investigating general characteristics and emotional intelligence of college student majoring in Radiological Science. The results showed that, in terms of general characteristics, age affects overall self-esteem, sex and school record affect a social self-esteem, and health affects self-esteem within the family as well as overall and social self-esteem.