We present high-resolution radial velocity (RV) measurements of K2 giant HD 66141 from December 2003 to January 2011 using the fiber-fed Bohyunsan Observatory Echelle Spectrograph (BOES) at Bohyunsan Optical Astronomy Observatory (BOAO). We find that the RV measurements for HD 66141 exhibit a periodic variation of 480 days with a semi-amplitude of 146 m/s. We do not find the correlation between RV variations and a chromospheric activity indicator (H line). The Hipparcos photometry as well as bisector velocity span (BVS) also do not show any obvious correlations with RV variations. Thus, Keplerian motion is the most likely explanation, which suggests that the RV variations arise from an orbital motion. Assuming a possible stellar mass of 1.5 $M{odot}$, for HD 66141, we obtain a minimum mass for the planetary companion of 7.4 MJup with an orbital semi-major axis of 1.4 AU, and an eccentricity of 0.07. We support that planet occurrence rate around evolved stars is more than 10 % (Dollinger et al. 2009) as well as more massive stars do form significantly more massive planetary companions (Johnson et al. 2007; Lovis & Mayor 2007; Dollinger et al. 2009).