Background: This study was performed to identify what effect plyometric exercise with application of kinesio taping gives on muscle activity and power of lower limb. Methods: In order to conduct research, total 14 male students at G university located Gwangyang city were randomly assigned; 7 for experimental group (with kinesio taping application) and 7 for control groups(without kinesio taping application) were conducted with box drill, one of the plyometric exercise 5 times a week for 4 weeks. Muscle activities were measured by using electrodiagnosis equipment on quadriceps and gastrocnemius. Collected data was analyzed by using Windows SPSS version 19.0. Results: Muscle activities show statistically significant differences (p<.05) both before and after exercise in experimental and control groups in terms of vastus medialis, rectus femoris, vastus lateralis and lateral gastrocnemius. However, only medial gastrocnemius shows statistically significant differences in experimental group compared before and after exercise. Sargent jump for measuring power shows that only experimental group presents statistically significant differences (p<.05). Two groups show that vastus medialis, vastus lateralis, lateral gastrocnemius and medial gastrocnemius only in muscle activities show statistically significant differences (p<.05) after exercise. Conclusion: The result of this survey indicates that plyometric exercise is effective to improve muscle activity and power of lower limb, especially, the group who exercises with application of kinesio tape is more effective than the other group with no tape application. Therefore, it is considered that plyometric exercise with tape is more effective to improve power and muscle strength.