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Magnetic Sensor-Based Detection of Picoliter Volumes of Magnetic Nanoparticle Droplets in a Microfluidic Chip
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  • Magnetic Sensor-Based Detection of Picoliter Volumes of Magnetic Nanoparticle Droplets in a Microfluidic Chip
  • Magnetic Sensor-Based Detection of Picoliter Volumes of Magnetic Nanoparticle Droplets in a Microfluidic Chip
저자명
Jeong. Ilgyo,Eu. Young-Jae,Kim. Kun Woo,Hu. XingHao,Sinha. Brajalal,Kim. CheolGi
간행물명
Journal of magnetics
권/호정보
2012년|17권 4호|pp.302-307 (6 pages)
발행정보
한국자기학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

We have designed, fabricated and tested an integrated microfluidic chip with a Planar Hall Effect (PHE) sensor. The sensor was constructed by sequentially sputtering Ta/NiFe/Cu/NiFe/IrMn/Ta onto glass. The microfluidic channel was fabricated with poly(dimethylsiloxane) (PDMS) using soft lithography. Magnetic nanoparticles suspended in hexadecane were used as ferrofluid, of which the saturation magnetisation was 3.4 emu/cc. Droplets of ferrofluid were generated in a T-junction of a microfluidic channel after hydrophilic modification of the PDMS. The size and interval of the droplets were regulated by pressure on the ferrofluid channel inlet. The PHE sensor detected the flowing droplets of ferrofluid, as expected from simulation results. The shape of the signal was dependent on both the distance of the magnetic droplet from the sensor and the droplet length. The sensor was able to detect a magnetic moment of $2{ imes}10^{-10}$ emu at a distance of 10 ${mu}m$. This study provides an enhanced understanding of the magnetic parameters of ferrofluid in a microfluidic channel using a PHE sensor and will be used for a sample inlet module inside of integrated magnetic lab-on-a-chip systems for the analysis of biomolecules.