Purpose: The aim of this study was to investigate gender differences in risk factors and sleep, depression, and mobility of Korean elderly with and without low back pain and sciatica. Methods: Data were derived from the 2011 Korean National Survey on Older Adults. Participants included 10,674 community-dwelling elderly. The group of elderly subjects with low back pain and sciatica and the group of elderly subjects without low back pain and sciatica were compared according to gender. Result: Age, monthly income, exercise, arthritis, osteoporosis, and providing caring support were significant risk factors for low back pain and sciatica in elderly male subjects. On the other hand, monthly income, living arrangement, arthritis, osteoporosis, providing caring support, and television watching time were significant risk factors in elderly female subjects. Significant differences in depression and mobility according to low back pain and sciatica were observed in both genders. Conclusion: Risk factors for low back pain and sciatica in elderly differed according to gender. Low back pain and sciatica showed an association with depression and mobility. These findings should be considered in planning for nursing intervention for low back pain and sciatica.