In the present study, three-dimensional transient numerical simulations were carried out to improve the performance of a vehicle paint drying process. In order to describe the movement of a vehicle, the techniques of moving boundary condition and multiple reference flames (MRF) were used. For the validation of the numerical analysis, the predicted temperature on the surface of a vehicle was compared to the experimental data, and a good agreement was achieved. With validated numerical procedure, various operating conditions of the temperature and the flow rate of the supply air were investigated to improve the drying performance of the facility. It is shown that the optimization of the operating condition can lead to energy savings and faster line speed of the production.