There have been some study characterizing monoids by homological classification using the properties around projectivity, injectivity, or regularity of acts. In particular Kilp and Knauer([4]) have analyzed monoids over which all acts with one of the properties around projectivity or injectivity are regular. However Kilp and Knauer left over problems of characterization of monoids over which all regular right S-acts are (weakly) at, (weakly) injective or faithful. Among these open problems, Liu([3]) proved that all regular right S-acts are (weakly) at if and only if es is a von Neumann regular element of S for all $s{in}S$ and $e^2=e{in}T$, and that all regular right S-acts are faithful if and only if all right ideals eS, $e^2=e{in}T$, are faithful. But it still remains an open question to characterize over which all regular right S-acts are weakly injective or injective. Hence the purpose of this study is to investigate the relations between regular right S-acts and weakly injective right S-acts, and then characterize the monoid over which all regular right S-acts are weakly injective.