Performance of a liquid rocket thrust chamber with regenerative cooling scheme has been numerically analyzed using in-house CFD code which can predict combustion/cooling performance and provide nozzle design parameters. This paper investigates trade-offs between combustion and cooling performance with varying amount of fuel directly injected into the chamber wall to form cooling films and mixture ratios for the peripheral injectors. Further efforts to verify/improve the simulation methodology including comparison with the firing test results are planned to make it a reliable tool to optimize the film cooling and other major design parameters.