Objectives : This study was done for reporting effect of moxibustion therapy on the degenerative arthritis of knee joint with osteochondroma. Methods : Two patient with degenerative arthritis of knee joint with osteochondroma was treated by moxibustion therapy. We applied moxibustion therapy three times a day for 12 days(three days per week). To investigate effectiveness of treatment we used visual analogue scale, Korean Western Ontario and McMaster Universities. Results : 1. The moxibustion therapy deceased knee joint pain. 2. As a result of evaluation by visual analogue scale, Korean Western Ontario and McMaster Universities the score marked lower than before treatment and after treatment. Conclusion : Moxibustion therapy decreased knee joint pain that patient have degenerative arthritis of knee joint with osteochondroma.