LED lighting systems that combine lighting capability, emotional and physiological characteristics are required for lighting source and multifunctional applications. In this work, Simulation studies using optical analysis software packages, Light Tools, are presented. This is done to estimate the uniformity ratio of illuminance and photosynthetic photon flux density (PPFD) of the periodic 2D lattice arrangements, such as square, diamond, two-way bias quadrangular, hexagonal, and Kagome lattices, under the same transmissivity, absorptance and reflectivity. It has been found out that the two-dimensional Kagome lattice arrangement exhibited high uniformity ratio of illuminance and PPFD compared to other lattices. Accordingly, these results can be used to guide a design and improve the lighting environment which in turn would maximize the uniform distributions of illuminance.