This paper considers a non-identical parallel machine scheduling problem with sequence and machine dependent setup times. The objective of this problem is to determine the allocation of jobs and the scheduling of each machine to minimize makespan. A mathematical model for optimal solution is derived. An in-depth analysis of the model shows that it is very complicated and difficult to obtain optimal solutions as the problem size becomes large. Therefore, two meta-heuristics, genetic algorithm (GA) and a new population-based evolutionary meta-heuristic called self-evolution algorithm (SEA), are proposed. The performances of the meta-heuristic algorithms are evaluated through compare with optimal solutions using randomly generated several examples.