This study focused on comparing macroscopic characteristics of DME and diesel fuel experimentally. DME fuel is one of the most promising alternative fuels because of its superiority in atomization characteristic and clearness in terms of exhaust gas compared with existing fossil fuels. In addition, DME fuel has high cetane number so it could be applied to compression ignition engine. However because DME fuel exists in gas phase at room temperature and atmospheric pressure, and it corrodes rubber parts of fuel line, DME fuel is hard to apply to commercial vehicles. To establish knowledge about DME fuel and furthermore, to develop commercial DME vehicles such as passenger cars, many research have been proceeded steadily. The present study, by comparing spray characteristics of DME fuel to those of diesel fuel, improved atomization characteristics in DME were revealed. Injection quantity measurement and spray visualization experiment were progressed and it was revealed that DME fuel shows small injection quantity than that of diesel fuel and axial development of spray in terms of spray tip penetration decreases when DME fuel was injected.