The purpose of this study was to approve the effects of nursing simulation-based education on problem solving process and self-efficacy for nursing students. The nursing students of 244 participated the nursing simulation-based education of 60 hours. The questionnaire survey on problem solving process and self-efficacy were conducted 2 time(before education, after education) to the nursing students. The data were analyzed by the SPSS 12.0 program. The results were as follows; There was a statistically significant increase in problem solving process(t=2.637, p=.012) but no statistically significants self-efficacy(t=0.135, p=.743) effects of nursing simulation-based training in nursing college students. There was a significant positive correlation between problem solving process and self-efficacy(r=0.737, p=.017). In conclusion, the study found that nursing simulation-based education for nursing students may increase problem solving process but no effective self-efficacy.