Transition prediction results are validated with experimental data obtained from a transonic wind tunnel for the KU109C airfoil. A Reynolds-Averaged Navier-Stokes code is simultaneously coupled with the transition transport model of Langtry and Menter and applied to the numerical prediction of aerodynamic performance of the KU109C airfoil. Drag coefficients from the experiment are better correlated to the numerical prediction results using a transition transport model rather than the fully turbulent simulation results. Maximum lift coefficient and drag divergence at the zero-lift condition with Mach number are investigated. Through the present validation procedure, the accuracy and usefulness of both the experiment and the numerical prediction are assessed.