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저자명
김신근,윤연진,이영만,이태선,최동원,송윤정,박준우,최동주,Kim. Sin-Guen,Yoon. Youn-Jin,Lee. Young-Man,Lee. Tae-Sun,Choi. Dong-Won,Song. Yun-Jung,Park. Jun
간행물명
대한악안면성형재건외과학회지
권/호정보
2012년|34권 4호|pp.233-238 (6 pages)
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대한악안면성형재건외과학회
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Purpose: To evaluate the effect of silvernanopartilce treated implants on the bone formation and osseointegration. Methods: Silvernanoparticle was produced using an anodic oxidation method. The size of silvernanoparticle ranged from 3.5 nm to 5.9 nm. To check the effect of the capability of osseointegration of silvernanoparticle coated Implant, 32 implants (16 piece of Implant treated with nanoparticle, and 16 piece of Implant was not treated for control) were placed at both the tibia of 8 New Zealand white rabbits. After 4 weeks, 4 rabbits were sacrificed and the removal torque was measured for comparison of the osseointagration ability. Further, 4 rabbits were sacrificed and sliced samples were made. H&E stain was done for microscopic finding. Results: The removal torque of the experimental group was $102.37{pm}30.54$ N/cm, and the control group was $73.30{pm}19.97$ N/cm. It was statistically significant (P<0.001). Microscopic finding also shows extinguish results in silvernanoparticle treated implants. Bone formation rate of the experimental group was 43.94% and the control group was 7.58%. It was observed to be statistically significant (P=0.017). Bone to implant contact rate of the experimental group was 58.09%, and the control group was 19.43%. It was found with statistical significance (P<0.001). Conclusion: The silvernanopartilce treated implant shows a better capability of bone regeneration and osseointegration than the non-treated one. Technology to produce smaller particles would make silver more useful and safer.