To schedule a Reconfigurable Manufacturing Cell (RMC), reconfiguration and setting decisions should be made first. Those decisions, together with characteristics of production orders, affect attainable performance of a system. So an integrative approach is required considering all decisions and characteristics rather than dealing with each of them separately. Pallet-fixture allocation, as a decision problem in setting, which determines the number of pallets to be equipped with each fixture type to produce different types of products, has rarely been investigated. In this study, several pallet-fixture allocation rules are proposed including both simple and novel ones. Then system performance is investigated through various combinations of setting and scheduling decisions (rules) for given system configurations and production orders, via simulation. The result shows that one of proposed pallet-fixture allocation rules which considers both configuration and order characteristic outperforms the others, justifying the necessity of an integrative approach in the RMC operation.