In this study the investigation of large deflections subject in compliant mechanisms is presented using homotopy perturbation method (HPM). The main purpose is to propose a convenient method of solution for the large deflection problem in compliant mechanisms in order to overcome the difficulty and complexity of conventional methods, as well as for the purpose of mathematical modeling and optimization. For simplicity, a cantilever beam of linear elastic material under horizontal, vertical and bending moment end point load is considered. The results show that the applied method is very accurate and capable for cantilever beams and can be used for a large category of practical problems for the aim of optimization. Also the consequence of effective parameters on the large deflection is analyzed and presented.