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서지반출
The impact of beam angle configuration of intensity-modulated radiotherapy in the hepatocellular carcinoma
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  • The impact of beam angle configuration of intensity-modulated radiotherapy in the hepatocellular carcinoma
  • The impact of beam angle configuration of intensity-modulated radiotherapy in the hepatocellular carcinoma
저자명
Kim. Sung Hoon,Kang. Min Kyu,Yea. Ji Woon,Kim. Sung Kyu,Choi. Ji Hoon,Oh. Se An
간행물명
Radiation oncology journal : ROJ
권/호정보
2012년|30권 3호|pp.146-151 (6 pages)
발행정보
대한방사선종양학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
서지반출

기타언어초록

Purpose: This treatment planning study was undertaken to evaluate the impact of beam angle configuration of intensity-modulated radiotherapy (IMRT) on the dose of the normal liver in hepatocellular carcinoma (HCC). Materials and Methods: The computed tomography datasets of 25 patients treated with IMRT for HCC were selected. Two IMRT plans using five beams were made in each patient; beams with equidistance of $72^{circ}$ (Plan I), and beams with a $30^{circ}$ angle of separation entering the body near the tumor (Plan II). Both plans were generated using the same constraints in each patient. Conformity index (CI), homogeneity index (HI), gamma index, mean dose of the normal liver (Dmean_NL), Dmean_NL difference between the two plans, and percentage normal liver volumes receiving at least 10, 20, and 30 Gy (V10, V20, and V30) were evaluated and compared. Results: Dmean_NL, V10, and V20 were significantly better for Plan II. The Dmean_NL was significantly lower for peripheral (p = 0.001) and central tumors (p = 0.034). Dmean_NL differences between the two plans increased in proportion to gross tumor volume to normal liver volume ratios (p = 0.002). CI, HI, and gamma indices were not significantly different for the two plans. Conclusion: The IMRT plan based on beams with narrow separations reduced the irradiated dose of the normal liver, which would allow radiation dose escalation for HCC.