Hemorrhagic shock is a common cause of death in emergency rooms. Early diagnosis of hemorrhagic shock makes it possible for physicians to treat patients successfully. Therefore, the purpose of this study was to select an optimal survival prediction model using physiological parameters for the two analyzed periods: two and five minutes before and after the bleeding end. We obtained heart rates, mean arterial pressures, respiration rates and temperatures from 45 rats. These physiological parameters were used for the training and testing data sets of survival prediction models using an artificial neural network (ANN) and support vector machine (SVM). We applied a 5-fold cross validation method to avoid over-fitting and to select the optimal survival prediction model. In conclusion, SVM model showed slightly better accuracy than ANN model for survival prediction during the entire analysis period.