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Human Skin Safety Test of Green Tea Cell Extracts in Condition of Allergic Contact Dermatitis
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  • Human Skin Safety Test of Green Tea Cell Extracts in Condition of Allergic Contact Dermatitis
  • Human Skin Safety Test of Green Tea Cell Extracts in Condition of Allergic Contact Dermatitis
저자명
Kim. Hyun-Kyu,Choi. Sun-Young,Chang. Hui-Kyoung,Baek. Seok-Yun,Chung. Jin-Oh,Rha. Chan-Su,Kim. Beom-Joon,Kim. Myeung-Nam
간행물명
Toxicological research
권/호정보
2012년|28권 2호|pp.113-116 (4 pages)
발행정보
한국독성학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Various kinds of positive effects of green tea extracts had been studied for long time which included anti-inflammation, anti-aging, and cardiometabolic effects. Although topical steroid and non-steroidal calcineurin inhibitors may control clinical symptoms of allergic contact dermatitis, some of patients also present allergic reaction to these topical agents. Therefore, we have tried green tea extracts for managing this skin disorder with expectation of anti-inflammatory effect without potential side effects including skin irritation and toxic responses. The toxicity test of green tea extract also did not show any sign of irritation in the skin throughout the test period. Moderate severity of allergic contact dermatitis presented satisfactory clinical outcome at second week follow-up which was final visit of outpatient. This result mean that green tea extract has a positive effect for managing allergic contact dermatitis but its potency and efficacy seem to be so not strong enough to control moderate severity allergy skin lesion. In this pilot study, we were able to conclude that green tea cell extracts might be applied for potential anti-inflammatory soaking without skin toxicity.