Objectives : Ethereal soul and Corporeal soul are very important part of mental activities that have researched and studied not only by ancient medical scientists but also by philosophers and thinkers in historical literature. Methods : There are some differences between ethereal soul and corporeal soul in terms of meaning, generative process, organs and the effects over the human body although they have been studied for a long time and have influenced on each other. Results : The perception of ethereal soul and corporeal soul are considerably limited in Korean medicine compared to their contribution of biological activities. The relationship of the positive and negative, yin and yang, is not even classified. So there is a general lack of understanding of ethereal soul and corporeal soul in oriental medicine course. Conclusions : Therefore, this thesis is designed for discussing the origin and relation of ethereal soul and corporeal soul. Also it would be explained the effect in terms of sleeping that is related Ethereal soul and Corporeal soul.