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Assessment of physical stability and photoprotective activity of topical formulations added with calendula oil
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  • Assessment of physical stability and photoprotective activity of topical formulations added with calendula oil
  • Assessment of physical stability and photoprotective activity of topical formulations added with calendula oil
저자명
Mishra. Arun K.,Mishra. Amrita,Chattopadhyay. Pronobesh
간행물명
Oriental pharmacy and experimental medicine : OPEM
권/호정보
2012년|12권 1호|pp.35-40 (6 pages)
발행정보
경희한의학연구센터
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

In the present work, the changes on physical properties (pH, viscosity, flow index and tixotropy) of topical formulations were evaluated following addition of calendula oil containing flavonoids. Also the photoprotective effect of these topical formulations were evaluated against ultra violet rays (UVR) induced sunburn in terms of sun protection factor (SPF). Formulation added with sun flower oil was used to compare the physical stability and photoprotective activity. Formulations added with calendula oil exhibited an average pH 7.2 and pseudoplastic behavior. The tixotropy values for formulations F3 and F4, after addition with calendula oil were found to be statistically decreased when compared with FS and Fb. The rheological parameters were constant during the study and the rheograms exhibited no sign of instability when studied at $4^{circ}$, $27^{circ}$ and $40^{circ}C$ on different days of storage. The F3 and F4 samples showed statistically higher SPF (14 and 15 respectively) when compared with Fb (without active sunscreening agent). The highest SPF value 16 was recorded for FS (control formulation added with sun flower oil) while Fb showed lowest SPF vale 5.We concluded that F3, F4 and FS showed higher SPF and physical stability. This study of physical stability and photoprotectice activity of topical formulation can help in the development of sunscreen formulation.