Purpose: This study was designed to examine the effects of horticultural therapy program on state-anxiety, fatigue and quality of life (QoL) of among women cancer survivors. Methods: Quasi-experimental study was used with a nonequivalent control group pretest-posttest design. Data were collected from February to June, 2009. Participants consisted of 40 women cancer survivors in community. The experimental group participated in horticultural therapy program once a week for 18 weeks. Data were analyzed with SPSS/WIN 18.0 program using ${chi}^2$-test and t-test. Results: There were significant differences between the two groups in state-anxiety and QoL. Conclusion: The results of this study support that horticultural therapy program was effective in decreasing state-anxiety and improving QoL among women cancer survivors.