In this study, the treatment ability of the wastewater containing perchlorate by non-salt tolerant perchlorate reducing bacterial consortium (N-PRBC) was evaluated in a continuous stirred tank bioreactor (CSTR). To obtain the optimal operating condition the bioreactor was operated with the different wastewater empty bed retention time (EBRT). The treatment performance in the bioreactor could be maintained at 100 $mg-ClO_4{^-}L^{-1}$ up to a EBRT of 3 h, and the removal capacity in the CSTR was about 3.3 times higher than that in a batch operation. With a decrease from 9 h to 2 h in a EBRT, the volumetric perchlorate reduction rate was increased from 11.1 $mg-ClO_4{^-}L^{-1}h^{-1}$ to 50.0 $mg-ClO_4{^-}L^{-1}h^{-1}$, and the specific perchlorate reduction rates were increased from 3.01 $mg-ClO_4{^-}g-DCW^{-1}h^{-1}$. In conclusion, the treatment capacities in a CSTR were much better than those obtained in a batch operation.