This paper develops a method based on a semi-analytical/FEM model to predict the ground vibrations induced by high-speed train running through continuous girder bridge. The prediction method has two steps: the solution of reaction on top of pier and the solution of ground vibrations. The reaction on pier top is solved by the semi-analytical dynamic interaction model for train-track-continuous girder bridge system, taking the dynamic characteristics of train, track, and bridge into account. The solution of ground vibrations is accomplished by establishing the 3-dimensional pile foundation-soil finite element model and then applying the negative reaction force got from pier top to the pile foundation-soil model. The effectiveness of the presented model is verified by comparing with other existed results.