This study was conducted to estimate the stability of a quay wall in case of wave overtopping under the combined action of an earthquake and tsunami using limit equilibrium method. The tsunami force was calculated by using a numerical program called TWOPM-3D (3-D one-field Model for immiscible TWO-Phase flows). Especially, the wave force acting behind the quay wall after a tsunami wave overtopping was estimated by treating back fill as a permeable material. The stability of the quay wall was assessed for both the sliding and overturning modes under passive and active conditions. The variation in the stability of the quay wall with time was determined by parametric studies, including those for the tsunami wave height, seismic acceleration coefficient, internal friction angle of the soil, wall friction angle, and pore water pressure ratio. When the earthquake and tsunami were considered simultaneously, the tsunami induced wave overtopping increased the stability of the quay wall under the passive condition, but in the active condition, the safety factors decreased.