This study analyzes the relation between family strength, self-efficacy and career maturity of college students. The results from the study are based on surveys, using a questionnaire method, undertaken by students from the Jeonnam area. Data was analyzed using the SPSS 19.0 program and the statistics used for analysis were t-Test, ANOVA, Correlation and Regression. The study found the following results. First, the family strength of the subjects was above average. Second, family strength, self-efficacy, and career maturity showed differences in terms of gender, major satisfaction, career counselling and major area. Third, the correlation among family strength, self-efficacy, and career maturity were observed positively in almost all sub-categories. Forth, the effects of family strength on self-efficacy and career maturity were significant. Based on these results, it is suggested that family strength should be enhanced to improve self-efficacy and career maturity of college students.