In this paper, we optimize antenna locations for a distributed antenna system (DAS) with distributed antenna (DA) ports equipped with multiple antennas under per-DA port power constraint. Maximum ratio transmission and scaled zero-forcing beamforming are employed for single-user and multi-user DAS, respectively. Instead of maximizing the cell average ergodic sum rate, we focus on a lower bound of the expected signal-to-noise ratio (SNR) for the single-cell scenario and the expected signal-to-leakage ratio (SLR) for the two-cell scenario to determine antenna locations. For the single-cell case, optimization of the SNR criterion generates a closed form solution in comparison to conventional iterative algorithms. Also, a gradient ascent algorithm is proposed to solve the SLR criterion for the two-cell scenario. Simulation results show that DAS with antenna locations obtained from the proposed algorithms achieve capacity gains over traditional centralized antenna systems.