Dental computer-aided design (CAD) and computer-aided manufacturing (CAM) technology have rapidly progressed over the past 30 years. The technology, which can be used in the dental laboratory, the dental office and the form of production centers, has become more common in recent years. This technology is now applied to inlays, onlays, crowns, fixed partial dentures, removable partial denture frameworks, complete dentures, templates for implant installation, implant abutments, and even maxillofacial prostheses. Dentists and dental technicians, who want to use these techniques, should have certain basic knowledge about that. This article gives an overview of CAD/CAM technologies, histories and how it applies in prosthetic dentistry.