In this letter, a modified 802.11-based opportunistic spectrum access is proposed for single-channel cognitive radio networks where primary users operate on a slot-by-slot basis. In our opportunistic spectrum access, control frames are used to reduce the slot-boundary impact and achieve channel reservation to improve throughput of secondary users. An absorbing Markov chain model is used to analyze the throughput of secondary users. Simulation results show that the analysis accurately predicts the saturation throughput.