Objective: The objective of this study is designing an optimal hand tool through maximum grip force study accordance to the hand grip span. Background: In order to prevent musculoskeletal diseases, studies on hand tool design are proceeding based on grip strength, finger force, and contribution of individual finger force on total grip strength. However, experimental apparatus using a tool that is actually used in work place was almost non-existent. Method: 19 males were participated in an experiment. Using the load cell inserted real plier, finger force, grip strength, and subjective discomfort rate of both hands (dominant and non-dominant) were measured in 5 different hand grip span(45mm, 50mm, 60mm, 70mm, and 80mm). Results: There was significant difference(p<0.001) of total grip strength, individual finger force and subjective discomfort rating according to various hand grip span(45, 50, 60, 70, and 80mm). Also, statistically significant different(p<0.001) was shown between the dominant hand and non-dominant hand. In addition, individual finger force in maximum grip was in order of middle finger, ring finger, index finger, and little finger. Conclusion: Optimal grip span of pliers that exerting maximum grip strength is 50~60mm. Application: This finding is expected to be used for designing proper pliers.