There have been many studies on biofilter process regarding satisfactory water quality and the operational conditions of Recirculating Aquaculture Systems (RAS). For effective nitrification processes, it is necessary to dynamically identify and apply nitrifying microorganisms. Physical, chemical and biological processes concerning biofilms can be applied and influential factors including substrate, dissolved oxygen concentrations, organic matter, temperature, pH, alkalinity, salinity and mixing velocity intensity need to be considered. Also, designing and managing the process based on the dynamic interpretation of these factors are prerequisites for engineering applications of the biofilter process. This paper draws on current literature on the kinetics of nitrification of biofilms in the biofilter process. Influential factors for nitrification are crucial during the biofilter process and are expected to be critical in informing the design and operation of recirculating aquaculture systems.