This study was carried out to investigate the effect of slurry composting and biofiltration (SCB) liquid manure application on shoot growth, fruit qualities and soil chemical properties in peach orchard. SCB liquid manure was fertigated ten times from April to October in SCB plot, whereas chemical fertilizer was treated two times as basal and additional fertilizers in control plot. The shoot growth, leaf nitrogen and potassium content, soil exchangeable K, fruit weight and yield were higher in SCB plot than in control. Soluble solid content and acidity, soil organic matter, soil available phosphate and soil exchangeable Mg showed no significant difference between treatments, and the leaf calcium and magnesium content were lower in SCB plot than in control. In conclusion, fertigating SCB liquid manure in peach orchard has positive effects on fruit weight and yield, and it is suggested that periodical soil testing is needed because of the possibility of K accumulation in SCB liquid manure treated soil when the orchard is fertigated based on the soil nitrogen content.