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Long-term results of forward intensity-modulated radiation therapy for patients with early-stage breast cancer
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  • Long-term results of forward intensity-modulated radiation therapy for patients with early-stage breast cancer
  • Long-term results of forward intensity-modulated radiation therapy for patients with early-stage breast cancer
저자명
Ha. Boram,Suh. Hyun Suk,Lee. Jihae,Lee. Kyung-Ja,Lee. Rena,Moon. Byung In
간행물명
Radiation oncology journal : ROJ
권/호정보
2013년|31권 4호|pp.191-198 (8 pages)
발행정보
대한방사선종양학회
파일정보
정기간행물|ENG|
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이 논문은 한국과학기술정보연구원과 논문 연계를 통해 무료로 제공되는 원문입니다.
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기타언어초록

Purpose: To observe long-term clinical outcomes for patients with early-stage breast cancer treated with forward intensity-modulated radiation therapy (IMRT), including local control and clinical toxicities. Materials and Methods: We retrospectively analyzed a total of 214 patients with stage I-II breast cancer who were treated with breast conserving surgery followed by adjuvant breast radiation therapy between 2001 and 2008. All patients were treated using forward IMRT. The whole breast was irradiated to a dose of 50 to 50.4 Gy followed by an 8 to 12 Gy electron boost to the surgical bed. Results: The median age was 46 years (range, 21 to 82 years) and the medial follow-up time was 7.3 years (range, 2.4 to 11.7 years). Stage T1 was 139 (65%) and T2 was 75 (35%), respectively. Ipsilateral breast recurrence was observed in 3 patients. The 5- and 10-year local control rates were 99.1% and 97.8%, respectively. The cosmetic outcome was evaluated according to the Harvard scale and 89.4% of patients were scored as excellent or good. Conclusion: The whole breast radiation therapy as an adjuvant treatment using a forward IMRT technique showed excellent long-term local control as well as favorable outcomes of toxicity and cosmesis.