This work investigated the effects of engine speed and injection timing on combustion and emissions characteristics in a partially premixed charge compression ignition (pPCCI) engine fueled with DME. pPCCI engine especially has potential to achieve more homogeneous mixture in the cylinder, which results in lower NOx and smoke emission. In this study single cylinder engine was equipped with common rail and injection pressure is 700 bar. Total injected fuel mass is 64.5 $mm^3$ per cycle. The amount of pilot injection of the entire injection 12.5% is tested. Results show that NOx emission is decreased while IMEP is increased as the retard of injection timing. Besides, NOx emissions are slightly rised as well as IMEP is increased with the increase of engine speed.