The variation of systematic bias errors in the wind tunnel testing has been studied. A Design of Experiments(DOE) approach to an experimental study of fuselage drag and stability characteristics of a helicopter configuration was applied. When forces and moments measured in one time block differ significantly from measurements made in another time block under assumption that sample observations can be expected to yield same results within permissible measuring errors. The practical implication of this paper is that the systematic error can not be assumed not to exist. The those error reduction could be achieved through the process of randomization, blocking, and replication of the data points.