In engineering practices, the superstructure was analyzed under a fixed boundary condition and the foundation was designed by considering the loading condition of superstructure. It may result in overestimation of forces, the bending moment, settlement of superstructure and foundation. In this study, an interactive analytical method is proposed for the interaction between the superstructure and the piled raft. The overall objective of this study is focused on the application of interactive analysis method for predicting behavior of entire structures. And a series of numerical analyses are performed to verify the interactive analysis routine in comparison to the unified analysis method. Through the comparative studies, it is found that the iterative and interactive analysis gave similar results of settlement and raft bending moment compared with those of finite element analysis. And it is also found that the proposed design method considering interaction between superstructure and foundation is capable of predicting reasonably well the behavior of entire structures. It can be effectively used to the design of a superstructure-piled raft foundation system.