To investigate numerically the effects of geometry and location of vertical opening on the thermal and chemical fire characteristics in full-scale under-ventilated compartment fires, the ventilation factor ($Asqrt{h}$) to estimate a theoretical maximum inflow of ambient air and the mass loss rate in a heptane pool fire were fixed for all cases. It was shown that variations in door geometry affected significantly the change in thermal and chemical characteristics inside the compartment. Variations in window location resulted in the complex change in additional fire characteristics including the fire duration time and recirculating flow structure. These results were analyzed in details by the multi-dimensional flow and fire characteristics including the vent flow and fuel/air mixing phenomena.