This paper describes effects of infill walls on behavior of RC frame with low strength, including numerical modeling, modal testing and finite-element model updating. For this purpose full scaled, one bay and one story RC frame is produced and tested for plane and brick in-filled conditions. Ambient-vibration testis applied to identify dynamic characteristics under natural excitations. Enhanced Frequency Domain Decomposition and Stochastic Subspace Identification methods are used to obtain experimental dynamic characteristics. A numerical modal analysis is performed on the developed two-dimensional finite element model of the frames using SAP2000 software to provide numerical frequencies and mode shapes. Dynamic characteristics obtained by numerical and experimental are compared with each other and finite element model of the frames are updated by changing some uncertain modeling parameters such as material properties and boundary conditions to reduce the differences between the results. At the end of the study, maximum differences in the natural frequencies are reduced on average from 34% to 9% and a good agreement is found between numerical and experimental dynamic characteristics after finite-element model updating. In addition, it is seen material properties are more effective parameters in the finite element model updating of plane frame. However, for brick in-filled frame changes in boundary conditions determine the model updating process.