An 11-year-old female toco toucan (Ramphastos toco) kept in outdoor exhibit was presented with sudden onset of anorexia and hypodynamia. After routine physical examination, the patient was treated. However, the bird died that evening. Necropsy revealed moderate swelling of the liver with yellowish discoloration. Based on the gross pathology as well as histologic evidence of iron pigments accumulation throughout the hepatocytes, hepatic hemochromatosis was diagnosed.